Scientist
Quick answer
Astera Foundation is hiring a remote Senior Scientist (US-based) to develop next-generation protein representations and bioinformatic pipelines.
- Role
- Scientist
- Organization
- Astera Foundation
- Location
- Remote (US-based)
- Work setup
- Remote
- Level
- Senior
- Category
- Engineering & Technology
The role
Astera is seeking a scientist for the diffUSE Project to develop next-generation protein representations and bioinformatic pipelines.
What you'll do
- Build ensemble-aware protein representations that integrate PLM and LLM embeddings with experimentally derived structural heterogeneity for functional prediction
- Design, develop, and maintain large-scale bioinformatic pipelines capable of processing and managing complex, high-dimensional datasets
- Fine-tune or architect ML models to capture sequence-structure-function relationships, with a focus on dynamic and conformational features
- Synthesize diverse data sources spanning evolutionary history, binding affinity, allostery, and functional annotations to improve model performance and biological relevance
- Collaborate closely with experimental partners to ground computational representations in real biological measurements
What it takes
- PhD in bioinformatics, computational biology, machine learning or a related field
- Strong understanding of protein structure and function
- Experience building large bioinformatic pipelines and managing high-dimensional datasets
- Proficiency in fine-tuning or modifying ML models (e.g., transformer-based architectures)
- Familiarity with protein language models (ESM, AlphaFold, etc.) is a plus
- Collaborative, team-oriented mindset
What you'll bring
Frequently asked questions
Where will the job be located?
The position is remote and US-based.
What is the compensation for this role?
Compensation is not specified in the posting.
What are the key qualifications required for this role?
Key qualifications include a PhD in bioinformatics, computational biology, machine learning or a related field, strong understanding of protein structure and function, experience building large bioinformatic pipelines, proficiency in fine-tuning ML models, and a collaborative mindset.
How can I apply for this position?
Interested candidates should submit their application through the Astera Foundation's recruitment portal or email their resume to [[email protected]].
How to apply
Apply directly on Astera Foundation's site. We link straight through — no resume parsing, no profile to fill out.
This listing is aggregated from a third-party source and its summary may be auto-generated, so details can be inaccurate or out of date. ForGood is not the employer and is not liable for the content — please verify everything on Astera Foundation's official posting before applying.