ForGood
AF
Astera Foundation

Scientist

LocationRemote (US-based)
SetupRemote
LevelSenior
Posted5d ago
Engineering & Technology

Quick answer

Astera Foundation is hiring a remote Senior Scientist (US-based) to develop next-generation protein representations and bioinformatic pipelines.

Role
Scientist
Organization
Astera Foundation
Location
Remote (US-based)
Work setup
Remote
Level
Senior
Category
Engineering & Technology

The role

Astera is seeking a scientist for the diffUSE Project to develop next-generation protein representations and bioinformatic pipelines.

What you'll do

  • Build ensemble-aware protein representations that integrate PLM and LLM embeddings with experimentally derived structural heterogeneity for functional prediction
  • Design, develop, and maintain large-scale bioinformatic pipelines capable of processing and managing complex, high-dimensional datasets
  • Fine-tune or architect ML models to capture sequence-structure-function relationships, with a focus on dynamic and conformational features
  • Synthesize diverse data sources spanning evolutionary history, binding affinity, allostery, and functional annotations to improve model performance and biological relevance
  • Collaborate closely with experimental partners to ground computational representations in real biological measurements

What it takes

  • PhD in bioinformatics, computational biology, machine learning or a related field
  • Strong understanding of protein structure and function
  • Experience building large bioinformatic pipelines and managing high-dimensional datasets
  • Proficiency in fine-tuning or modifying ML models (e.g., transformer-based architectures)
  • Familiarity with protein language models (ESM, AlphaFold, etc.) is a plus
  • Collaborative, team-oriented mindset

What you'll bring

PhD in bioinformaticscomputational biologymachine learning or a related fieldStrong understanding of protein structure and functionExperience building large bioinformatic pipelines and managing high-dimensional datasetsProficiency in fine-tuning or modifying ML models (e.g.

Frequently asked questions

Where will the job be located?

The position is remote and US-based.

What is the compensation for this role?

Compensation is not specified in the posting.

What are the key qualifications required for this role?

Key qualifications include a PhD in bioinformatics, computational biology, machine learning or a related field, strong understanding of protein structure and function, experience building large bioinformatic pipelines, proficiency in fine-tuning ML models, and a collaborative mindset.

How can I apply for this position?

Interested candidates should submit their application through the Astera Foundation's recruitment portal or email their resume to [[email protected]].

How to apply

Apply directly on Astera Foundation's site. We link straight through — no resume parsing, no profile to fill out.

Apply now →

This listing is aggregated from a third-party source and its summary may be auto-generated, so details can be inaccurate or out of date. ForGood is not the employer and is not liable for the content — please verify everything on Astera Foundation's official posting before applying.